Geriatrics & Healthy Aging

5+ hour, 9+ min ago   (943+ words) A surplus of insulating brain cells, low on one protective protein, tracked the steepest cognitive decline in adults followed since childhood. After 70, memory and quick thinking slow down for most people, and the usual explanation is that the brain’s wiring…...

1+ hour, 15+ min ago   (636+ words) The earliest fingerprints of an aging brain may be visible not in memory lapses or mood changes, but in an unexpected place: the gut....

2+ hour, 55+ min ago   (56+ words) Physical activity has become one of the most widely recommended interventions for people with neurodevelopmental disorders, a family of conditions that includes autism spectrum disorder, attention-deficit/hyperactivity disorder, intellectual developmental disorder, and specific learning, communication and motor disorders. Clinical guidelines…...

4+ hour, 59+ min ago   (542+ words) Alzheimer’s disease has long been portrayed as a story written in the cortex, the wrinkled outer layer of the brain where memory and thought reside. But a new study published in Nature Communications suggests that the opening chapters of that…...

5+ hour, 8+ min ago   (77+ words) For the millions of people who survive a stroke or traumatic brain injury each year, the most stubborn obstacles to recovery are often invisible. While paralysed limbs and unsteady gait attract immediate clinical attention, the cognitive aftershocks—faltering attention, scrambled…...

5+ hour, 21+ min ago   (641+ words) A single protein long suspected of linking the ageing brain to neurodegenerative disease is stepping into the spotlight....

6+ hour, 3+ min ago   (672+ words) Frontotemporal dementia has long been described as a disease of personality and language, but one of its rarest and most elusive forms has remained stubbornly difficult to characterize....

6+ hour, 35+ min ago   (668+ words) The pathological proteins that accumulate in the aging human brain are not amorphous debris. They are highly ordered molecular assemblies, and their precise atomic architecture can determine which neurodegenerative disease a patient develops, how fast it progresses, and how it…...

9+ hour, 32+ min ago   (688+ words) The complement system, a sprawling network of plasma and membrane-bound proteins long regarded as little more than a first-response killing machine against microbes, is now recognized as one of the most consequential players in neurology. A comprehensive new review published…...

9+ hour, 43+ min ago   (573+ words) For patients with amyloidosis, the difference between receiving the right treatment and the wrong one can hinge on a deceptively simple question: which protein is actually forming the deposits? Amyloidosis is not one disease but a family of disorders in…...